that’s not possible in one instance of EZdrummer 2, no.
You can load 2 instances of EZdrummer 2 and unload everything but the Toms with preset ‘A’ in instance 1 and then load preset ‘B’ in instance 2 and unload the Toms.
Feed both instances the same MIDI and it will be like you had everything in one instance with two presets applied.
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